Expect More. Lycopene is highly synergistic with docetaxel at inhibiting the growth of prostate cancer in mice. Although dietary lycopene may offer protection against cancers of the lung, breast, bladder, stomach, mouth or prostate, supplemental lycopene may worsen the effects of prostate cancer in men who already have the disease, MedlinePlus notes. Other causes include urogenital infections, congenital and genetic anomalies, immunologic factors, and endocrine disorders. Wang Y, Cui R, et al. Interestingly, in the tomato products, 80-90% of the lycopene is in the trans (linear) configuration, while in the blood and prostate isomers 47% and 80 %, respectively, were in the cis (bent) form. Sloan Kettering Institute Research Education & Training Careers MSK Direct Make an Appointment Refer a Patient Learn About Cancer & Treatment About Us Patient Portal: MyMSK Donate Now For Adult Patients / Free standard shipping with $35 orders. [2] From observations, every single prepared formulation had an emblematic dose-dependent cytotoxic effect on the prostate cancer cells. Additionally, lycopene showed that it could modulate the signaling pathways and their protein for the treatment or prevention of prostate cancer. Apoptosis is a natural process of programmed cell death. Several studies indicate that lycopene may be of value for prostate cancer prevention and treatment. It helps the prostate. DOI: 10.1097/MD.0000000000001260 Abstract Prostate cancer (PCa) is a common illness for aging males. Dosing Lycopene administered as a pure compound has been studied in clinical trials at dosages of 7 to 75 mg/day. It is a natural supplement with varied health benefits and particularly beneficial for prostate and bladder health. This PDQ summary has sections about the use of specific foods and dietary supplements to prevent or treat prostate cancer: Calcium Green Tea Lycopene Modified Citrus Pectin Pomegranate Selenium Soy Vitamin D Vitamin E Combination Therapies Other Prostate Health Supplements The role of lycopene for prostate health has been questioned recently. For male reproductive health specifically, it helps protect prostate cells from oxidative stress and promotes improved sperm quality and motility. The absorbed lycopene is mostly stored in the liver, adrenals, and prostate. Still, more research is needed to confirm this effect for lycopene . In 1995, a seven-year study of 45,000 volunteers showed that lycopene helps to reduce the risk of certain degenerative prostate disease. Although no established authority has offered official recommendations regarding lycopene dosage, Dr. Edward Giovannucci, a professor of nutrition and epidemiology at the Harvard School of Public. dose, timing of dose, intake of other foods at the time of . UCLA lab tests showed that lutein reduced prostate cancer cell growth by 25 percent while lycopene reduced cell growth by 20 percent. put together from 8 isoprene systems. New blood vessel formation is critical to feed prostate cancers, and . It contains natural ingredients that have been shown to be beneficial in research: lycopene from Lycored Lycopene whole tomato extract, soy isoflavones from Novasoy whole soybean extract, vitamin D3, and natural low-dose selenium and vitamin E. Men who have lycopene-rich diets tend to have lower risks of prostate cancer (7). Results: One patient manifested a tumor response with a 50% or greater confirmed decline in serum prostate-specific antigen level, yielding a response rate of 2%. Early stages of BPH should be treated with 160 milligrams twice a day. What are the dosages of lycopene? Enter your search keyword. Dose-response analysis of circulating lycopene concentrations and risk of prostate cancer. The best use of the herb is for preventing swelling after prostate surgery. General Dosing Guidelines Pure compound 13-75 mg/day orally Capsule 10-30 mg twice daily orally Prostate Cancer 15 mg twice daily orally Oral Leukoplakia 4-8 mg/day orally Specific lycopene supplement (LycoRed) Preventing Exercise-Induced Asthma 30 mg/day orally SLIDESHOW . A study published last May in published in the journal Cancer Epidemiology Biomarkers & PreventionJournal of . . . Call us at 833-347-1665 to make an appointment. However, results have been inconclusive. Summary So, i'm currently on a daily 50 MG dose of casodex and every 90 days they pump 23.5 Mg of lupron in me. PLoS One. fruit and application of K 2 O @ 375 Kg K 2 O ha -1 along with recommended doses of N and P was found to be the best dose for high quality tomato fruit. Among the best beverages for prostate health are both green tea and hibiscus tea. 2015 Sep 15;10(9):e0137427. Scientific literature documents lycopene's antioxidant activity and its use in cancer prevention (breast and prostate), as well as its use in the prevention of cardiovascular disease. Better prostate health in 5 easy steps sup on tea. Most guys don't pay much attention to prostate health. Dosages from 10. Choose from Same Day Delivery, Drive Up or Order Pickup. A few studies have suggested benefits of lycopene for exercise-induced asthma [1] and benign prostatic hyperplasia. . Thus indicating that both nutrients together help protect against prostate cancer better than either nutrient alone. One study tracked 26 men slated for prostate-cancer surgery. (2004) . Researchers linked high lycopene intakes to a 9% lower likelihood of developing prostate cancer. Daily intakes of 921 mg per day appeared most beneficial. The plant has white flowers that produce yellow berries that turn black when they're ripe. It belongs to the carotenoid family of substances, and because it consists entirely of carbon and hydrogen, is also classified as a carotene. This may explain the wide variation in the dose used in the identified studies, which. The key to using vitex successfully is taking only the recommended dose, since overdoses cancel out the anti-testosterone effects of the herb. OBJECTIVES: Determine any dose limiting toxicities and the maximum tolerated dose of lycopene administered orally as a food based delivery system in healthy male subjects 18-45 years of age for the chemoprevention of prostate cancer. New findings from the ECOG E3805 study presented . Shop by category. The solid black line and 2 dotted black lines are the restricted cubic spline for the published relative risks (RRs) and 95% confidence intervals (CIs); the short dash straight line is the linear fitting curve used for linear and nonlinear analysis. Background Many epidemiologic studies have investigated the association between carotenoids intake and risk of Prostate cancer (PCa). Shop by category. The purpose of this study is to determine the maximum tolerated dose (MTD) of lycopene given in combination with docetaxel. This scenario would give you about 20 mg of lycopene [ 51 ]. The role of tomato products and lycopene in the prevention of prostate cancer: a meta-analysis of observational studies. But they should. A significant reduction of the oxidative stress inside the cell. Research has found that lycopene-rich foods can help suppress carcinogens, slow cancer cell growth, and reduce cell damage (6). 3 Skip to main content. Additionally, lycopene may suppress growth signals in human prostate cancer and breast cancer cells . Read reviews and buy Swanson Lycopene - Natural Supplement Promoting Prostate Health, Heart Health, & Supports Blood Pressure Within the Normal Range - Mens Health Supplement - (60 Softgels, 20mg Each) at Target. Lycopene Dosage. HANDINESS AND DOSAGE: Lycopene is formulated along with the multivitamins. Are There Any Side Effects It is related to beta- carotene and gives some vegetables and fruits (e.g., tomatoes) a red color. Advanced: Daily Deals; Brand Outlet . The ideal dosage of lycopene and the optimum dosage formulation are not known. Methods We conducted a systematic review and dose-response meta-analysis of dietary intake or blood concentrations of carotenoids in relation to PCa risk. The growth inhibitory effect of lycopene on human prostate cancer cells observed in this study suggests a possibly important role for lycopene as an . The Prostate The prostate is the male reproductive gland located below the bladder. Prostate cancer. 3 Lycopene 20mg Per Serving 200 Capsules Supplement Antioxidan Prostate Exp 4/2025. Lycopene supplements may have unknown side effects or medication interactions when taken in high doses. . See amounts of lycopene in foods like tomatoes and grapefruit, dosage for lycopene supplements, safety and side effects. Lycopene and enlarged prostate health is on the forefront of many research studies involving the prostate gland. Lycopene is a compound found in tomato and grapefruit. Lycopene is protective in controlling the induction and metastatic phase of the prostate disease [ 1 ]. Daily intakes of 9-21 mg per day appeared most beneficial. REFG3 Taking lycopene by mouth might slightly reduce the risk of developing prostate cancer. Blood levels should be checked after . One of the biggest benefits of lycopene is that it is an antioxidant and protects the body from free radical stress that can damage DNA and other cell structures. The antioxidant properties help balance free radical activity in the body 6 and, in doing so, may reduce the risk of certain diseases. Pay Less. Researchers linked high lycopene intakes to a 9% lower likelihood of developing prostate cancer. What's new is the knowledge that LycoVit inhibits prostate growth in general. Cancer Lett. Furthermore, it is not known whether the observed effects on normal . S. T., Daneshvar, B., and Jakobsen, J. Dose-response effects of lycopene on selected drug-metabolizing and antioxidant enzymes in the rat. Effect of Carotene and Lycopene on the Risk of Prostate Cancer: A Systematic Review and Dose-Response Meta-Analysis of Observational Studies. Lycopene has been found to effectively suppress the progression and proliferation, arrest in-cell cycle, and induce apoptosis of prostate cancer cells in both in-vivo and in-vitro conditions. These berries can be dried to make an herb that's been used for conditions like prostateissues, urinary. Lycopene is a powerful. Lycopene as a dietary supplement is a potent antioxidant used to help prevent cancer, heart disease, and macular degeneration. Puritan's Pride Lycopene is popular and the dosage is high, at 40 mg per capsule. . Prostate-cancer treatment. It might also slightly reduce the risk of prostate cancer returning. However, a dose of 5 mol/L lycopene led to a significant accumulation of cells in the G0/G1 phase (71% vs. 56%; P < 0.05) and significantly fewer cells in the S phase . Prostate 2.4 is to be taken once per day (2 capsules) with food. Lycopene has been shown to induce apoptosis in cancer cells. Some lycopene supplementation research conducted on men has shown positive results in treating infertility in men. Lycopene supplements are safe and well tolerated. Tomatoes contain a powerful antioxidant called lycopene. [2] Where to Get Lycopene Most of the info out there focuses on tomatoes, canned or cooked tomatoes to be precise. People take lycopene for preventing heart disease; "hardening of the arteries" ( atherosclerosis ); and cancer of the prostate, breast, lung, bladder, ovaries, colon, and pancreas. Dr Oz said that taking Saw Palmetto 160 mg twice a day can help with enlarged prostates and prostate health. Cancer Epidemiol Biomarkers Prev. Adopt a prostate-friendly eating plan. The capsule design isn't the cleanest, but as far as lycopene supplements that are both high dosage and delivered dissolved in a lipid solution, it's your best bet by a long ways. Another great food to consume for prostate health is the almighty tomato. Studies have suggested that lycopene can inhibit the growth of the prostate gland in patients diagnosed with an enlarged prostate and reduce the risk of other prostate conditions such as prostate inflammation and prostate cancer. Furthermore, compared with the lowdose lycopene group, the highdose lycopene group significantly reduced the levels of inflammatory cytokines above. Determine the pharmacokinetics of this regimen in this population. Studies have found a weak link between high dietary lycopene intake from tomato products and a reduced risk of prostate cancer. About Dr Oz Fans Lycopene has been identified as an antioxidant agent with potential anticancer properties. 3. We summarized the data from 34 eligible studies (10 cohort, 11 . In a care study conveyed by The British journal of urology, men with prostate cancer are subjected to surgery . It allows LycoVit to be re-positioned on the food supplement market," said Sievert. Uses of Lycopene. The lycopene in supplements is about as easy for the body to use as lycopene found in food. Lycopene is a potent antioxidant that has been found highly beneficial for prostate health. Higher serum lycopene levels in the blood have been associated with up to an 80% reduction in the risk of developing prostate cancer. ..It arrives in only 2 days.. Lycopene for Prostate Health: Dr Oz said that eating lycopene rich foods like tomatoes and watermelon daily can help to shrink the prostate too. 10 Natural Treatments for Enlarged Prostate In This Article 1 Herbs 1.1 Saw Palmetto 1.2 Stinging Nettle 1.3 Pygeum 2 Other Plant-Derived Remedies 2.1 Lycopene 2.2 Isoflavones 3 Vitamins and Minerals 3.1 Selenium 3.2 Beta Carotene 3.3 Vitamin D 3.4 Vitamin E 3.5 Vitamin K Many in-vitro, human, and animal studies suggest that lycopene can decrease production of prostate cancer cells. Volume 38 4.6/5 - (111 votes) High doses of lycopenethe red pigment in tomatoeswere put to the test to see if it could prevent precancerous prostate lesions from turning into full-blown cancer. Lycopene bioavailability can be decreased by ageing, and some of the pathological states, such as cardiovascular diseases (CVDs) [ 7 ]. Efficacy was typically higher when the interventions were started earlier and lasted longer. The end-of-study prostate lycopene concentration was was 3.5-, 3.6-, and 2.2-fold higher in the tomato soup, sauce, and juice consumers, respectively. In lycopenetreated groups, lycopene reduced significantly the levels of inflammatory cytokines of prostatic tissue including IL1, IL2, IL6, TNF, MCP1, and MIP1. Understand . Lycopene, found abundantly in red or pink fruits and vegetables, may reduce the risk of developing an enlarged prostate or cancer. 7. Tomato products or lycopene have strong anti-cancer effects in a number of animal models of prostate cancer. Saw Palmetto Dosage For Prostate For the treatment of BPH ( Benign Prostatic Hyperplasia ) the recommended dose is starting with 320 milligrams three times daily for four months, then dropping down to 320 milligrams once a day. Overview Lycopene is a type of organic pigment called a carotenoid. I use brands containing Lycomato, which is lycopene extracted from tomatoes, as that is the kind I see most often used in studies . 2. . Lycopene, Supplement for Prostate and Heart Health Support* 10 Mg Softgels, 100 Count by Puritan's Pride. Isolation procedures for lycopene were first reported in 1910, and the structure of the molecule was figured out by 1931. Find the best quality lycopene supplements and review cost comparisons of popular brands. lycopene levels are more divulged to prostate cancer and those with sound diet of lycopene have a less risk of prostate cancer. Because there is a lack of research and data on lycopene dosage, the Institute of Medicine (IOM) has not set an upper limit for dosage . Data are shown as mean SD. Lycopene | Memorial Sloan Kettering Cancer Center Ready to start planning your care? Prostate Health Complex contains Lycopene, Pumpkin Seed and Saw Palmetto, nutrients that contain phytonutrients and fatty acids that may help maintain a healthy prostate. There is no association between lycopene and the risk of bladder and colon cancers. Data regarding diet and prostate cancer are accumulating and randomized controlled trials are currently underway which will ultimately yield evidence on which to base recommendations regarding dietary regimens, functional foods, and supplement-use. 6-30-2000;154:201 . Several animal studies, mostly using transgenic rat models have documented reduced tumour growth [23-25] and altered gene expression counteracting carcinogenesis . When lutein and lycopene were combined, prostate cancer cell growth was reduced by 32 percent. Lycopene suggested uses include for cancer, preventing atherosclerosis, cardiovascular disease, prostate cancer, human papillomavirus ( HPV) infection, cataracts, asthma, antioxidant, and as an anti-inflammatory. Supersmart Lycopene is a carotenoid that is naturally found in tomatoes. Daily intakes of 9-21 mg per day appeared most beneficial ( 13 ). Features : Provides antioxidant properties that help cells fight damaging free radicals in the body. This dose can then be used for subsequent phase II or phase III studies. ingest supplements lessen tension changing things. . In conclusion, this study indicates that lycopene at a dose of 15 mg/d for 6 mo, may inhibit disease progression and may ameliorate symptoms in BPH patients. Lycopene is a potent antioxidant and has antiproliferative, pro-apoptotic properties in the prostate. Prostate cancer is one of the top three cancers in men. Subscribe to Videos Discuss Republish View Transcript Its antioxidant effect can help protect prostate cells as well as the DNA from oxidative damage. A recent human study showed that high intake of dietary lycopene, largely from tomatoes, was strongly correlated with less blood vessel formation in prostate cancers. in 2020, supplementation of lycopene had positive effects on cancer markers in 25 (93%) of the studies. It is classified as a nonprovitamin A carotenoid because it cannot be converted to vitamin A. Contains a 25- to 50-day supply of easy-to-swallow softgels, Helps Support Prostate Health. The effects of lycopene on normal prostate development and organ function need further clarification. Th ey are formulated as . In 27 clinical trials reviewed by M. Mirahmadi, et al. Lycopene is a balanced tetraterpene, i.e. Lycopene 20mg Per Serving 200 Capsules Supplement Antioxidan Prostate Exp 4/2025. As a treatment for prostate cancer, supplemental lycopene didn't show major benefit [Source: Jatoi].However, another study has shown patients taking 15 mg of supplemental lycopene, three weeks before surgery to remove the prostate, had improvements in cancerous lesions and decreases in the PSA score (a blood test used to monitor prostate cancer) [Source: Kucuk]. This blend offers nutrition that's especially needed by the male body, including saw palmetto, lycopene, pumpkin seeds, zinc and more. Eating tomatoes: You can increase lycopene blood levels and get the antioxidant benefits with just a pint of tomato juice and about 4 oz of tomato sauce per day. The optimal dose to achieve a biologically active lycopene concentration in the human prostate is unknown. I take double the dose it recommends-- because I want to see if it can help me..Well by the 7th day, I START to feel a little better in that . Moreover, it can be found in other body parts (e.g., brain and skin) in a lower concentration [ 6 ]. Vitamin D 2000 u daily is a reasonable starting dose for men in the prostate cancer age group. Several mechanisms of action of lycopene in prostate cells have been described. Learn whether lycopene intake is associated with a decreased risk of cancer, such as prostate cancer and colon cancer. Lose weight through exercising. Lycopene, a pigment found in tomatoes, . Lycopene can help treat benign prostatic hyperplasia and prevent its progression to prostate cancer by the mechanisms listed above. This does not mean that there is no upper limit. Determine the dose range of this regimen to . High-dose lycopene supplements can reduce the size of prostate tumors, and may be useful as an adjunct therapy. Lycopene supplements: 60 mg/day of lycopene for three months improved various measures of health. Lyopene has numerous health-promoting benefits. The effect of lycopene has been found to be by inhibiting DNA synthesis that could significantly decrease the proliferation and growth of cancer cells in primary PEC (prostate epithelial cancer). Life Extension Mega Lycopene Check price at Amazon (15 mg Lycopene + 333 IU . The data suggest that lycopene may not be the only compound in tomatoes with anti-prostate cancer activity. One of the finest things you can do to support prostate health is to exercise and lose weight. 5. This action slows prostate growth, but can also interfere with erections. It has been used as an antioxidant to slow damage to cells. Researchers linked high lycopene intakes to a 9% lower likelihood of developing prostate cancer. Reply (1) Report. Find out if lycopene helps with infertility and more. Tomato sauce reduces the risk of developing advanced prostate cancer by 35%. Patients were prescribed a lycopene-rich tomato supplement at a lycopene dose of 15 mg twice daily. 30, or 75 mg of lycopene to study its effect on prostate cancer and other diseases. Lycopene was effective in most model systems, but the response was dependent on dose, duration, and type of carcinogenic process. "Lycopene significantly decreased the growth of cells in a dose-dependent manner when cells were incubated for 24, 48, 72, or 96 hours (F = 3.150, 11.27, 54.51, and 297.5, respectively; P <.05). $35.20 QTY: ADD TO SUBSCRIPTION Shout-out to the prostate gland. Lycopene (prostate) . Due to the capability of nanoparticles to control the release of encapsulated lycopene, there was a high cytotoxicity of the prepared formulations [ 30 ]. Keywords: Lycopene does not selectively interfere with PSA levels, which is important to allow early detection of PCa during . Fifteen took 30 milligrams of natural-source lycopene daily. Studies investigating the relation between lycopene and PCa risk have produced inconsistent results.